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KMID : 0604520220480030189
Journal of the Society of Cosmetic Scientists of Korea
2022 Volume.48 No. 3 p.189 ~ p.196
Evaluation of the Potential of Nitrogen Plasma to Cosmetics
Lee So-Min

Jung So-Young
Brito Sofia
Heo Hyo-Jin
Cha Byung-Sun
Lei Lei
Lee Sang-Hun
Lee Mi-Gi
Bin Bum-Ho
Bin Bum-Ho
Abstract
Plasma refers to an ionized gas that is often referred to as ¡°the fourth phase of matter¡±, following solid, liquid, and gas. Plasma has traditionally been utilized for industrial applications such as welding and neon signs, but its promise in biomedical fields such as cancer treatment and dermatology has lately been recognized. Indeed, due to its beneficial effects in promoting collagen production, improving skin tone, and eliminating harmful bacteria in the skin, plasma treatment constitutes an important target for dermatological research. In this study, a plasma device for cosmetic manufacturing based on nitrogen, the main component of the atmosphere, was designed and assembled. Moreover, nitric oxide (NO) was selected since is easier to follow and evaluate than other nitrogen plasma active species, and its contents were measured to perform a quantitative and qualitative evaluation of plasma. First, an injection method, using different proximities labeled ¡°sinking¡± and ¡°non sinking¡± treatments, was performed to test the most efficient plasma treatment method. As a result, it was observed that the formulation obtained by a non sinking treatment was more effective. Furthermore, toner and ampoule were selected as cosmetics formulations, and the characteristics of the formulation and changes in the injected plasma state were observed. In both formulations, the successful injection of NO plasma was 2 times higher in toner formulation than ampoule formulation, and it gradually decreased with time, having dissipated after a week. It was confirmed that the nitrogen plasma used did not affect the stability of the toner and ampoule formulations at low temperature (4 ¡ÆC), room temperature (25 ¡ÆC), and high temperature (37 ¡ÆC and 50 ¡ÆC) conditions. The results of this study demonstrate the potential of plasma cosmetics and highlight the importance of securing the stability of the injected plasma.
KEYWORD
atmospheric pressure plasma source, nitrogen plasma, anti-aging, wound healing, plasma activated
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